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This metabolite provides a PDE selectivity profile just like sildenafil and an in vitro potency for PDE5 close to 50% on the father or mother drug. Plasma concentrations of this metabolite are about 40% of People seen for sildenafil, so that the metabolite accounts for about 20% of sildenafil's pharmacologic outcomes.Hearing: Instances of sudden lo

VIAGRA should not be used with REVATIO or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such bey Adcirca [tadalafil])sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes yaşama be a sign of a serious eye sıkıntı called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking